Main Office:300 Shire Way Lexington, MA 2421
Shire Human Genetic Therapies, Inc. |
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Visa Rank: 6,995 | LCA for H-1B: 8 | LC for Green Card: 2 | Prevailing Wage Determination: 6 | ✔ All petitions certified!
Update(1/9/26): In fiscal year 2025, Shire Human Genetic Therapies filed 8 LCAs for H-1B visas, 2 labor petitions for green cards, and 6 requests for prevailing wage determination.
Update(12/16/2025): We’ve recently added H-1B visa approval and denial history from USCIS(2017–2025) and H-1B visa petition locations to provide a more complete view of employment-based immigration. Previously, our data included only Labor Condition Applications (LCAs) certified by the U.S. Department of Labor.
For example, in fiscal year 2025, Shire Human Genetic Therapies filed 8 Form I-129 petitions for H-1B visas. Of these, 8 were approved and 0 were denied.
Number of Employees: 945
Founded: 1994 - Main Office: Lexington, MA - NAICS Industry: Materials and Chemical Manufacturing
H-1B Dependent: No - Willfull Violator: No
Shire Human Genetic Therapies, Inc. filed 8 labor condition applications (LCAs) for H-1B visas and 2 labor certifications (LCs) for green cards during fiscal year 2025. Shire Human Genetic Therapies was ranked number 6,995 among all visa sponsors. Additionally, all petitions were certified!
Before Shire Human Genetic Therapies can hire foreign workers, whether permanently or temporarily, it must submit labor certifications to the Department of Labor (DOL). These certifications confirm compliance with wage requirements for the specified job locations.The reports below summarize Labor Condition Applications (LCA) for H-1B visas and Labor Certifications (LC) for green cards filed by Shire Human Genetic Therapies. This data represents only the number of applications submitted and does not guarantee visa approvals or worker hires.
The LCA data includes applications for various purposes: new employment, continuation or changes to previously approved employment, new concurrent employment, changes in employer, and amended petitions. Typically, only LCAs for new employment require an H-1B visa cap if the employer is not cap-exempt.For example, Shire Human Genetic Therapies submitted 26 LCAs and LCs during fiscal year 2025. However, this figure does not necessarily reflect the number of foreign workers hired, as visa applications can be denied. Additionally, employees renewing or transferring H-1B visas or changing work locations may need to file new LCAs.
The DOL generally certifies more than three times the number of foreign worker requests compared to the H-1B visas issued by USCIS. Therefore, there is no direct correlation between the number of workers certified by the DOL and the H-1B visas issued by the United States Citizenship and Immigration Services (USCIS).
Overview of the backgrounds of foreign workers sponsored by Shire Human Genetic Therapies for permanent employment, highlighting up to 12 categories in each field along with the number of workers. The fields include citizenship, colleges attended, degrees earned, fields of study, and visa status.
Summary of Labor Condition Applications (LCAs) for H-1B visas and Labor Certifications (LCs) for green cards filed by Shire Human Genetic Therapies. The data includes new employment, continuation or changes to previously approved employment, new concurrent employment, changes in employer, and amended petitions.
This table summarizes H-1B visa petition decisions made by the U.S. Citizenship and Immigration Services (USCIS) or the U.S. Department of State, not the Labor Condition Applications (LCAs) certified by the Department of Labor (DOL).
| Year | New Approval | New Denial | Continuation Approval | Continuation Denial | Change Employer Approval | Change Employer Denial | Total Approval | Total Denial | Total H-1B* |
|---|---|---|---|---|---|---|---|---|---|
| 2025 | 0 | 0 | 6 | 0 | 1 | 0 | 8 | 0 | 8 |
| 2024 | 2 | 0 | 5 | 0 | 3 | 0 | 12 | 0 | 12 |
| 2023 | 1 | 0 | 2 | 0 | 2 | 0 | 7 | 0 | 7 |
| 2022 | 2 | 0 | 0 | 0 | 4 | 1 | 12 | 1 | 13 |
| 2021 | 5 | 0 | 2 | 0 | 8 | 0 | 36 | 2 | 38 |
| 2020 | 8 | 0 | 1 | 0 | 12 | 1 | 29 | 1 | 30 |
| 2019 | 10 | 0 | 3 | 0 | 5 | 0 | 27 | 0 | 27 |
| 2018 | 11 | 1 | 6 | 0 | 25 | 0 | 49 | 1 | 50 |
| 2017 | 1 | 0 | 3 | 1 | 13 | 0 | 24 | 2 | 26 |
* Why are the numbers different? LCAs are a prerequisite to filing H-1B visa petitions, but not all certified LCAs lead to actual H-1B filings. Similarly, one LCA can support multiple visa petitions (e.g., for extensions, amendments, or changes in employer). Therefore, visa totals may differ significantly from LCA totals.
Moreover, employers sometimes use different names when submitting LCAs and H-1B visa petitions. This can cause discrepancies in our system.
To get a complete and accurate picture, please use the search function to explore both LCA and visa data.
Total H-1B includes all types of visa petitions: new employment, continuation, change of employer,
as well as other actions not listed in the table, such as concurrent filings and amendments.
| Year | H-1B Salary | Green Card Salary | Prevailing Wage |
|---|---|---|---|
| 2025 | $134,466 | $175,375 | $142,452 |
| 2024 | $139,256 | $182,767 | $108,192 |
| 2023 | $127,911 | N/A | $111,321 |
| 2022 | $131,688 | $156,036 | N/A |
| 2021 | $119,739 | $126,494 | N/A |
| 2020 | $120,658 | $114,475 | N/A |
| 2019 | $99,987 | $121,113 | N/A |
| 2018 | $111,320 | $109,578 | N/A |
| 2017 | $102,136 | $113,181 | N/A |
The salary figures shown represent the average proffered (offered) salaries reported by Shire Human Genetic Therapies on labor condition applications (LCA) for H-1B visas and permanent labor certification (PERM) for green cards. These are base guaranteed salaries and do not include bonuses, stock options, or other forms of compensation.
If Shire Human Genetic Therapies reported a salary range, we use the midpoint to calculate the average. Salaries submitted in hourly, weekly, or monthly terms are converted to an annualized figure based on a standard full-time schedule (e.g., 40 hours/week, 52 weeks/year).
Summary of the occupations and job titles of foreign workers sponsored by Shire Human Genetic Therapies for permanent employment, highlighting up to 12 roles in each field along with the number of workers. To increase your chances of receiving visa sponsorship, focus on positions that Shire Human Genetic Therapies has historically hired foreign workers for.
The individuals listed in this section are employees of Shire Human Genetic Therapies, Inc. authorized to represent the company in labor certification matters. They cannot be agents or attorneys unless they are direct employees of Shire Human Genetic Therapies. Furthermore, they may not be Human Resources professionals directly involved in hiring or resume screening. In smaller companies, these representatives are often decision-makers, such as the president or operations director.
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Summary of the Top Locations with the Highest Number of Foreign Workers. The main office ranks as the primary worksite for foreign workers, hosting the largest number among all locations.
Main Office:300 Shire Way Lexington, MA 2421
This table summarizes H-1B visa petition decisions made by the USCIS or the U.S. Department of State since 2017. The city and state reflect the employer’s mailing address as listed on Form I-129 and may not represent the actual work location(s) of the beneficiary(ies).
| City | State | New Approval | New Denial | Continuation Approval | Continuation Denial | Change Employer Approval | Change Employer Denial | Total Approval | Total Denial | Total H-1B* |
|---|---|---|---|---|---|---|---|---|---|---|
| Chicago | IL | 3 | 1 | 5 | 1 | 13 | 0 | 28 | 3 | 31 |
| Lexington | MA | 35 | 0 | 22 | 0 | 50 | 2 | 157 | 4 | 161 |
| Cambridge | MA | 1 | 0 | 1 | 0 | 8 | 0 | 15 | 0 | 15 |
| New York | NY | 1 | 0 | 0 | 0 | 2 | 0 | 4 | 0 | 4 |
*Total H-1B includes all types of visa petitions: new employment, continuation, change of employer, as well as other actions not listed in the table, such as concurrent filings and amendments.
Yes, during past fiscal year, Shire Human Genetic Therapies has filed 8 LCAs for H-1B Visa positions.
Yes, during the past fiscal year, Shire Human Genetic Therapies has filed 8 LCs for employment based green card positions.
No, Shire Human Genetic Therapies is not an H-1B-dependent employer, meaning it does not have a high proportion of H-1B workers relative to its total workforce.
The most common roles for H-1B Visa positions are Senior Validation Engineer(3), Digital Analyst(2), Engineer Ii(2), Product Quality Lead(2), Regulatory Lead(2), Scientist(2). The most common roles for green card positions are Team Lead, Global Reg Affairs Device, Pdt(1), Sr Process Validation Engineer Ii(1), Senior Engineer Ii(1), Senior Disposition Quality Specialist(1), Associate Director, Quality Risk Management(1).
Number of Reviews: 4 - Average Review Score: 4.3 -
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